Oxygen Tension Regulates Pancreatic -Cell Differentiation Through Hypoxia-Inducible Factor 1
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چکیده
منابع مشابه
Oxygen Tension Regulates Pancreatic β-Cell Differentiation Through Hypoxia-Inducible Factor 1α
OBJECTIVE Recent evidence indicates that low oxygen tension (pO2) or hypoxia controls the differentiation of several cell types during development. Variations of pO2 are mediated through the hypoxia-inducible factor (HIF), a crucial mediator of the adaptative response of cells to hypoxia. The aim of this study was to investigate the role of pO2 in beta-cell differentiation. RESEARCH DESIGN AN...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2009
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db09-0891